Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease - Nature.com

3/3/2022 12:00:00 AM3 years 2 months ago
Genome-wide meta-analysis of SARS-CoV-2 susceptibility and severity phenotypes in up to 756,646 samples identifies a rare protective variant proximal to ACE2. A 6-SNP genetic risk score provides additional predictive power when added to known risk factors.
GWAS of SARS-CoV-2 infection identifies ACE2 association We performed GWAS of COVID-19 outcomes across 52,630 individuals with COVID-19 and 704,016 individuals with no record of SARS-CoV-2 infection… [+25960 chars]
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