Atherosclerosis Reduced in Mice by Deleting TRPM2 from Macrophages - Genetic Engineering & Biotechnology News

3/29/2022 12:00:00 AM3 years 1 month ago
by Julianna LeMieux, PhD
by Julianna LeMieux, PhD
The TRPM2–CD36 axis is found to be a molecular mechanism underlying atherogenesis and suggests TRPM2 as a potential therapeutic target.
Ischemic heart disease and stroke are the leading causes of mortality worldwide. One of the pathological features of atherosclerosis is the formation of foam cells after macrophages take up oxidized … [+3373 chars]
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