New UCI-led study lays foundation for establishing base editing as a one-time, durable treatment for inherited retinal degeneration - EurekAlert

A new University of California, Irvine-led study indicates base editing may provide long-lasting retinal protection and prevent vision deterioration in patients with inherited retinal degeneration, specifically in Leber congenital amaurosis (LCA) patients.

image: Here we show that in vivo correction of an Rpe65 mutation by adenine base editor (ABE) prolongs the survival of cones in LCA mouse model.view more  Credit: Nature Communications Irvine, CA –… [+5161 chars]

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