Double-stranded RNA induces bone loss during gum disease - EurekAlert

Bone decay and tooth loss from gum disease is triggered by a previously unknown interaction between double-stranded RNA and the cells involved in bone formation and dissolution.

image: TLR3 signaling activated by ds RNA [poly(I:C)] analogue induces the PGE2-mediated expression of RANKL that stimulates osteoclast formation and directly prolongs the life span of mature osteocl… [+6044 chars]

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