Preventing Attacked Cancer Cells from Repairing Membranes May Enhance Immunotherapy - Genetic Engineering & Biotechnology News

4/22/2022 12:00:00 AM3 yearsago
by Anjali A. Sarkar, PhD
by Anjali A. Sarkar, PhD
Repair of perforin pores enables target cells to resist cytolytic attack. This mechanism may be targeted to increase immunotherapy efficacy.
Cancer cells are adept at escaping death. One of the ways in which cancer cells prevent death from fatal attacks by cytotoxic T lymphocytes (CTLs) is by efficiently repairing damage to their cell mem… [+6414 chars]
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