Scientists implicate non-cardiac genes in congenital heart disease - Science Daily

Researchers show that three transcription factors -- GATA4, NKX2-5 and TBX5 -- interact with CHD4 inside the embryonic heart, recruit it for action, and uses CHD4 to play their roles in heart health and disease.

Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA -- a crucial regulatory step before proteins are created. Then, organs… [+3369 chars]

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