Researchers investigate self-regulation of an enzyme with critical cellular functions - ASBMB Today


5/24/2022 12:00:00 AM2 years 11 months ago
by Emily M. Overway

They found that one mechanism of CK1 activity, and thus one mechanism of regulation, is the self-phosphorylation of a conserved amino acid residue in its catalytic domain.

The lab of Kathy Gould at Vanderbilt University School of Medicine used a multidisciplinary approach that included structural biology, biochemistry and molecular biology to investigate the regulation… [+2447 chars]

full article...