Z-DNA Triggering Drug Kills Immunotherapy Resistant Melanoma by Mimicking Flu - Genetic Engineering & Biotechnology News


5/26/2022 12:00:00 AM2 years 11 months ago
by Anjali A. Sarkar, PhD

A candidate cancer drug triggers left-handed Z-DNA conformation and promises alternative approaches for immunotherapy resistant tumors.

In a new study, scientists have identified a small molecule candidate drug that triggers the formation of left-handed Z-DNA in cells that in turn activates a highly immunogenic programmed pathway of … [+5636 chars]

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