Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion - Nature.com

Macromolecular aggregates may have played an important role in the origin of life. Here, the authors report hydrophobic-cationic peptides that form insoluble aggregates, which reversibly accrete RNA on their surfaces, and enhance RNA polymerization by a riboz…

Selection of peptides to regulate the RPR activity Aiming to obtain new peptides that bind and regulate an RNA polymerase ribozyme (RPR ZLT, Fig. 1a), we first performed peptide selection by using t… [+26163 chars]

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