Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell | Communications Biology - Nature.com

Necroptosis of lung epithelial cells is regulated by aminopeptidase N levels in circulating plasma exosomes in patients and mice with sepsis-induced acute lung injury.

Patient recruitment and sample collection The study was approved by the Medical Ethics Committee of the Shenzhen Hospital of Southern Medical University (Shenzhen, China, approval ID: NYSZYYEC202000… [+17786 chars]

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