Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster - Nature.com

Circadian dysfunction is a potential driver of eye aging. Here the authors report that in conjunction with the core molecular clock transcription factor Clock, dietary restriction promotes rhythmic homeostatic mechanisms within photoreceptors to delay visual …

Experimental materials A full detailed description of the materials, primer sequences, software packages, and commercial assays used in this study are reported in Supplementary Data 7. Data was coll… [+30304 chars]

full article...