Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer - Nature.com

A genomic analysis of ductal carcinoma in situ (DCIS) samples with matched ipsilateral invasive breast cancer recurring later shows that around 18% of tumors were unrelated to the DCIS, and had distinct clonal origins.

This research complies with all relevant ethical regulations: The Sloane project, United Kingdom National Health Service Breast Screening Programme, was approved by the UK Health Research Authority (… [+23542 chars]

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