New research reveals unexpected function for basic DNA-based processes during chromosome folding - Phys.org
6/13/2022 12:00:00 AM2 years 10 months ago
by Science X staff
by Science X staff
New findings reveal an advanced, unexpected two-way communication between the function and organization of chromosomes in the cell nucleus. Previous research shows that the organization of chromosomal DNA into loops regulate gene reading (transcription) and c…
Depletion of the cohesin loader Scc2 in G2/M phase disrupts chromosome loop formation. (A) Normalized Hi-C contact maps (2-kb binning) showing cis interactions along the arm of chromosome XIV (150 to… [+4076 chars]
full article...