cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers - Nature.com

6/15/2022 12:00:00 AM2 years 10 months ago
The survival of cells with chromosomal instability (CIN) depends on the cGAS–STING pathway, in which IL-6 and its receptor have a key role; this vulnerability can be exploited to treat tumours that display CIN.