A plasmid system with tunable copy number - Nature.com

The range of available copy numbers for cloning vectors is largely restricted to the handful of ORIs that have been isolated from plasmids found in nature. Here the authors introduce a plasmid system that allow for the continuous, finely-tuned control of plas…

Model of ColE1 plasmid replication and copy number The molecular mechanisms that regulate plasmid copy number control have been well characterized26. In the ColE1 origin of replication, used extensi… [+32429 chars]

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