Ticagrelor and Aspirin Most Effective in First Week Poststroke for CYP2C19 Loss-of-Function Allele Carriers - Neurology Live

7/9/2022 12:00:00 AM2 years 9 months ago
by Marco Meglio
by Marco Meglio
The net clinical benefit with ticagrelor and aspirin over clopidogrel and aspirin treatment may be predominant in the first week, with additional small benefit in the second and third weeks for those with minor ischemic stroke or transient ischemic attack.
Secondary analysis data from the CHANCE-2 randomized clinical trial (NCT0407837) suggest that the benefit of dual antiplatelet therapy (DAPT) using ticagrelor (Brilinta; AstraZeneca) and aspirin is m… [+4549 chars]
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