Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing | Communications Biology - Nature.com

Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.

Molecular cloning of ACR variants For HEK-cell expression, mutations were introduced in previously described ACR constructs of GtACR165 (Addgene #85464) and PhobosCA11 (Addgene #98169) using the Qui… [+17133 chars]

full article...