Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses - PLOS

Anya Topiwala and colleagues investigate the observational and genetic associations of alcohol intake with measures of iron levels in the brain and liver, and cognitive function among UK Biobank participants.

Summary of findings Alcohol consumption, including at low levels, was observationally associated with higher brain iron in multiple basal ganglia regions. There was some evidence supporting a causal… [+11551 chars]

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