In CF, Molecular Glue May Help CFTR Protein Fold Correctly, Work... - Cystic Fibrosis News Today

7/18/2022 12:00:00 AM2 years 9 months ago
by Margarida Maia, PhD
by Margarida Maia, PhD
A study showed a type of molecule called a macrocycle can stabilize the CFTR/14-3-3 binding and improve CFTR function in cystic fibrosis.
A type of ring-shaped molecule called a macrocycle can help CFTR the faulty protein in cystic fibrosis (CF) go to the cells membrane, where it exerts its action, and work better in lab-grown cells ca… [+4544 chars]
full article...