There's a special place in Hevin for ER secretion - EurekAlert

Researchers from the University of Tsukuba have found that a mutation in the EF-hand motif in Hevin/Sparcl1 that has been associated with a familial case of autism spectrum disorder results in structural instability of the protein, causing endoplasmic reticul…

Researchers from the University of Tsukuba find that an autism-associated mutation in Hevin results in its retention in the endoplasmic reticulum and activates the unfolded protein response in cells … [+3534 chars]

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