Study reveals how the ovarian reserve is established - EurekAlert

Female fertility in mammals is limited by the ovarian reserve, the stock of follicles kept in an arrested state for years to decades. A new study reveals the mechanism that controls establishment of the ovarian reserve.

image: The PRC1 gene complex is needed to establish the ovarian reserve. Deletion of the PRC1 gene complex in mice led to death of primordial follicles in the ovary. Wild type mice at top, PRC1 delet… [+3704 chars]

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