Mechanism Discovered Behind Strongest Lupus Genetic Risk Factor |... - Lupus News Today
8/18/2022 12:00:00 AM3 years 6 months ago
by Marta Figueiredo, PhD, Marta Figueiredo, PhD
by Marta Figueiredo, PhD, Marta Figueiredo, PhD
Researchers have discovered the underlying mechanism of the strongest genetic risk factor of systemic lupus erythematosus (SLE).
The strongest genetic risk factor of systemic lupus erythematosus (SLE), HLA-DRB1*03:01, generates an abnormal protein that, in the presence of the pro-inflammatory interferon gamma (IFN-gamma), acti… [+5889 chars]
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