Researchers show how mutations in 'dark genome' cause pancreatic malformations: Mutations in EnhP is most clear-cut example to date of how disruptions in non-protein coding DNA elements cause disease - Science Daily

In the vast majority of diseases caused by mutations in a single DNA sequence, the disruption of a gene is to blame. However, many non-coding elements in the genome, which inhabit what is sometimes known as the 'dark genome' are also thought to play a role in…

Researchers at the Centre for Genomic Regulation (CRG) have identified a DNA sequence that is crucial for pancreatic differentiation and function -- and for the first time -- describe how it works.Pa… [+4481 chars]

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