Organoid Culture Optimized to Match Human Small Intestines - Genetic Engineering & Biotechnology News

A signaling mechanism that includes the helical cytokine IL-22 (interleukin-22) and the kinase mTOR (mammalian target of rapamycin), is required for human progenitor cells to differentiate into Paneth cells in the small intestines, a new study from Hubrecht I…

Organoid models of the small intestines are now a closer match to the cellular architecture of the human intestine, thanks to the work done by the Organoid group at Hubrecht Institute in the Netherla… [+3812 chars]

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